Fennel

Jan 2, 2025

Fennel: What is it?

  • Other names: Foeniculum vulgare.

Mechanism of action:

  • Fennel is a good source of vitamin C, potassium, plant flavanoids, and beta-carotene.

  • Vitamin C and flavanoids (discussed further in their own section) have antioxidant activity which in turn are anti-inflammatory.

  • Other compounds found in fennel seeds—including anethole and estragole—are thought to make it a possible galactogogue.

  • For this reason, fennel seeds/fennel seed oils are included in some lactation supplements, but there have not been large randomized trials to prove its efficacy.

  • One randomized trial testing the effects of curcumin and fennel essential oil on IBS symptoms also had positive results.

  • This study is discussed further in the evidence section.

Common indications/uses:

  • Fennel and fennel seeds are commonly used in a normal diet.

  • As noted above, the oils of fennel seeds have compounds which are thought to be beneficial to lactation.

Dosing:

  • 50 mg fennel essential oil was used in Portincasa et al., but fennel is otherwise used unmeasured in its vegetable form which is not concentrated.

Evidence:

  • Portincasa et al. studied the combination of curcumin and fennel in patients with IBS.

  • Curcumin has anti-inflammatory properties, and fennel has anti-spasmodic and anti-inflammatory effects which the authors wanted to assess together for improvement of IBS symptoms.

  • Over 30 days, patients in the experimental group reported improvement in their IBS symptoms and better quality of life.


Safety concerns:

  • Adverse reactions: Allergic reactions, photosensitivity.

Drug interactions:

  • Ciprofloxacin absorption, distribution, and elimination were affected by fennel ingestion in a small randomized study.


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